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Milk Thistle Phytosome - Solmarie
€27.90
BBD : 06/30/2027
Shipped on : 10 December 2025
Active liver support: Solmarie helps to regenerate and detoxify your liver from stress, medication, alcohol, and diet.
5x Better Absorption thanks to the patented phytosome process, with proven action of our extract supported by multiple scientific studies.
Box of 60 capsules. 1-month supply (2 capsules/day). Vegan.
Solmarie: Optimized Milk Thistle for a Detoxified, Protected, and Regenerated Liver
Your liver is the silent hero of your body, a vital organ that performs over 500 essential functions, from detoxifying toxins to regulating your metabolism. It is the pillar of your vitality and overall health.
However, it is constantly solicited and often mistreated by our modern lifestyle: chronic stress, persistent fatigue, dietary excesses (sugars, bad fats, alcohol), tobacco, exposure to environmental pollutants, and even certain medications can exhaust it. A tired liver doesn't always speak clearly, but signs can appear: persistent fatigue, a feeling of heaviness after meals, unexplained lower back pain, itchy skin without redness, pale stools, or persistent bad breath. If these warnings resonate with you, Milk Thistle is the reference plant for liver support.
Solmarie goes far beyond a simple Milk Thistle extract. We have reinvented its effectiveness to offer you a cutting-edge solution for deep detoxification and hepatic protection, thanks to unparalleled assimilation.
Milk Thistle: A Complete and Scientifically Validated Hepato-Protective Action
Milk Thistle is the most studied plant for liver health, recognized for its powerful virtues. Its main active ingredient, silybin, acts on several fronts to protect, detoxify, and regenerate your liver:
1. Detoxification and Anti-Toxin Shield:
Silybin acts as a barrier, preventing toxins from damaging liver cells. Moreover, it stimulates detoxification by increasing the production of glutathione, your body's "master antioxidant," essential for eliminating undesirable substances.
2. Anti-Inflammatory Action and Metabolic Support:
It helps to regulate inflammatory processes within the liver and provides valuable assistance in regulating blood sugar, thereby contributing to overall metabolic balance.
3. Powerful Hepatic Regeneration:
One of the most crucial roles of silybin is its ability to stimulate the regeneration of liver cells. It helps your liver repair itself and regain optimal functions, normalizing key markers such as transaminases (ALT) and gamma-GT.
Solmarie: The Phytosome Innovation for Exceptional Silybin Assimilation (Up to x5!)
The natural silybin from Milk Thistle is unfortunately very poorly assimilated by the body. To unleash its full potential, Solmarie incorporates the patented phytosome technology, a major scientific breakthrough. This process binds pure silybin (100% active silybin) to natural phosphatidylcholine. The latter acts as an "intelligent transporter," encapsulating the silybin and multiplying its assimilation by 5 compared to conventional extracts. Thus, silybin effectively reaches your liver for optimal action.
Evidence of Solmarie Phytosome's Superiority:
- Scientifically Proven Bioavailability: Rigorous studies have demonstrated this 5-fold superior assimilation, validated even in people with specific liver conditions, ensuring real and profound effectiveness.
- Unrivaled Purity and Quality: Each capsule of Solmarie guarantees 100% active silybin, the most beneficial compound of Milk Thistle.
- Visible Clinical Results: Patient studies have shown normalization of liver enzymes (ALT, gamma-GT) and significant improvement in liver health.
Why Choose Solmarie? A Commitment to Your Lasting Liver Well-being
Opting for Solmarie Milk Thistle Phytosome means choosing the most advanced and safest solution to actively support your liver. It can be consumed all year round, with no known side effects for the recommended dosage (1 to 2 capsules per day). Solmarie is your ideal ally to detoxify, strengthen, and protect your liver, and thus regain vitality and well-being daily.
For optimal effectiveness and lasting results, we recommend taking 2 Solmarie capsules per day, ideally on an empty stomach before meals. A course of at least 3 months is strongly recommended to allow your liver to regenerate deeply. Give your body the support it deserves!
Offer your liver the protection and vitality it deserves, choose Solmarie.
Why Choose Solmarie Over Another Milk Thistle Extract?
To experience the proven benefits highlighted by scientific studies, it's essential to use an extract that is both highly concentrated in active compounds and easily absorbed by the body (passing from the intestine into the bloodstream).
Solmarie contains 100% silybin, the liver-protecting substance that is five times more absorbable (bioavailable) than a standard silybin-rich extract.
This makes it the best option for obtaining all the benefits of Milk Thistle without needing to consume large quantities.
The positive effects of Milk Thistle only occur with extracts rich in silymarin, one of the seed's main components.
Silymarin contains 50 to 70% silybin, the most active substance for liver protection.
Therefore, it is crucial that silybin reaches the liver in sufficient quantities.
Solmarie stands out from other standardized high-silybin extracts (70 or 80%) because it contains 100% silybin, which is four to five times more absorbable than standard extracts, thanks to patented phytosome technology.
Pharmacokinetic studies have shown that the absorption of phytosome extract is five times higher than that of free herb extract at equivalent dosages.
Silybin itself is only moderately liposoluble, preventing it from effectively crossing the intestinal barrier. Phytosome technology binds silybin to phosphatidylcholine from soy, a natural substance that easily passes through the intestinal barrier. This bond allows both substances to enter the bloodstream and reach the liver efficiently.
What Effect Does Phosphatidylcholine Have on the Liver?
Phosphatidylcholine is a component of cell membranes. It is not only safe for the liver but can also aid in liver cell regeneration. It works synergistically with silybin to protect the liver.
Why Protect Your Liver?
The liver is the largest organ in the body, processing almost everything you eat, drink, or absorb through your skin.
It performs over 500 functions, including fighting infections, neutralizing toxins, producing proteins and hormones, regulating blood sugar, and aiding in blood clotting.
The problem is that the liver seems incredibly resilient until it fails, and despite scientific advancements, there are limited treatment options.
An unhealthy liver leads to fatigue and a reduced ability to defend against external threats. Therefore, it is crucial to care for it and prevent the body from becoming overloaded with toxins.
Why Use Milk Thistle for Liver Support Over Other Herbs?
Milk Thistle (Silybum marianum) is the most extensively studied medicinal herb for liver support. It helps maintain liver function and protects against toxins.
It is widely used to support recovery from serious illnesses or as a preventive measure.
By taking 1 to 2 capsules of Milk Thistle phytosome daily, you can easily follow the dosages recommended in scientific studies.
Box of 60 capsules (1-month supply)
Ingredients per daily serving of 2 vegetable capsules:
Milk Thistle (Sylibum Marianum) seed extract: 240 mg
Contains 80 mg of silybin bound to 160 mg of phosphatidylcholine through the patented phytosome process.
1 to 2 capsules daily, preferably before meals, as part of a minimum 3-month course or as a long-term treatment for enhanced effectiveness, unless otherwise directed by your healthcare professional.
When to Use Solmarie?
• To support healthy liver function
• To protect healthy liver cells and tissues
• When the liver has been overworked (due to diet, alcohol, or medication)
• As support for functional and pathological liver disorders
• During a detox regimen
• To naturally increase Glutathione levels
Additional Recommendations
- If you wish to support your digestion more comprehensively, you can pair Solmarie with probiotics.
- To further support the liver and also the gallbladder, you can combine Solmarie with Solumine Turmipure Gold BIO Curcumin.
- For a more comprehensive detox/purification regimen, you can combine Solmarie with Liposomal Glutathione.
Scientific Information
Milk thistle (Silybum marianum) is the most extensively studied herbal remedy for liver support.
It is used in cases of liver damage caused by alcohol abuse (such as fatty liver, hepatitis, and cirrhosis), acute and chronic viral hepatitis, or liver diseases induced by toxins, like prolonged use of tacrine (an Alzheimer's treatment), rifampicin and isoniazid (antibiotics), or acetaminophen (pain reliever). (1, 2, 3, 4, 5, 6, 7, 8)
Research has also demonstrated effects on kidney cells following exposure to common medications or chemotherapy drugs (acetaminophen, cisplatin, and vincristine) (9, 10).
Silymarin is known to aid cancer patients (liver, prostate, colon, and renal cell carcinoma) due to its anti-inflammatory, apoptosis-inducing, cell cycle-modulating, anti-angiogenic, anti-metastatic, and anti-inflammatory effects (11).
The beneficial impact of milk thistle is only observed when using silymarin-rich extracts. Silymarin, extracted from the seeds of milk thistle, is a mix of chemically related substances, including silybin, isosilybin, silychristin, and silydianin.
Among silymarin components, silybin stands out as the most active antioxidant and liver-protective agent. It is also the primary component, comprising 50 to 70% of silymarin (synonyms include silybin and silibinin).
Dried seed powder contains only 1.5 to 3% silymarin. An effective daily dose equates to about 420 mg of conventional silymarin, necessitating a standardized extract (for example, 70 to 80% silymarin).
However, a lower dose alternative exists: phytosomal silybin, where silybin is bound to phosphatidylcholine (a phospholipid) derived from soy. As a phytosome, silybin's intestinal absorption is 4.6 times higher in the bloodstream and 10 times higher in bile compared to regular silybin in conventional silymarin (12, 13).
The improved bioavailability of phytosomal silybin has been demonstrated in healthy volunteers, patients with liver cirrhosis, and those who have undergone gallbladder removal.
Ordinary silybin is harder to absorb due to its large molecular size and lower lipid solubility, which are necessary for passing through the intestinal wall and the cell membrane of enterocytes. The phytosomal technique enhances the absorption of silybin and other plant substances (14).
Phytosomal silybin not only ensures better absorption but also has enhanced liver-protective effects. The silybin-phosphatidylcholine phytosome provides two liver-protective agents: silybin and phosphatidylcholine, which work synergistically. Silybin, acting as an antioxidant and anti-inflammatory, repairs damaged liver cells, blocks toxin receptors, supports protein synthesis in liver cells, and inhibits scar tissue formation.
Phosphatidylcholine itself is a key component of cell membranes, meaning a damaged phospholipid in a liver cell membrane can be easily replaced by phosphatidylcholine from the phytosome (15).
The efficacy and safety profile of phytosomal silybin have been proven: clinical studies revealed significant liver function improvements, and a daily dose of 1085 mg of phytosomal silybin (well above the usual 80 to 160 mg/day) was well tolerated.
However, even a 120 mg/day dose yields positive results, and researchers suggest an ideal daily dose of 240 to 360 mg (2 to 3 capsules) to avoid side effects (16).
Scientific Studies on the Silybin-Phosphatidylcholine Complex in Solmarie
Liver Protection Against Non-Alcoholic Fatty Liver Disease and Hepatitis C
A multicenter, double-blind, placebo-controlled study over 12 months on 138 patients with documented non-alcoholic fatty liver disease (36 of whom had Hepatitis C) involved 94 mg of silybin and 194 mg of bound phosphatidylcholine daily (2 Solmarie capsules), plus 30 mg of vitamin E. The study showed significant improvements in liver enzyme levels, insulin resistance, and liver histology among treated patients. Additionally, 15% of patients normalized their BMI (compared to 2% in the placebo group), and those with Hepatitis C saw better fibrosis markers. (17)
Liver Protection in Chronic Hepatitis Patients
A placebo-controlled pilot study on 20 patients showed that 240 mg/day of milk thistle phytosome significantly reduced liver toxicity markers (AST, ALT, Gamma-GT, total bilirubin). Researchers concluded that milk thistle phytosome improves liver function, particularly in cell necrosis and membrane permeability. (18)
Liver Protection in Children Undergoing Chemotherapy for Acute Lymphoblastic Leukemia
A double-blind, placebo-controlled study on 50 children receiving chemotherapy found that administering 80 mg of bound silybin (2 capsules) daily for 28 days significantly lowered aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels by day 56. These enzymes are markers of liver toxicity. The silybin phytosome treatment did not interfere with chemotherapy effects. Researchers highlighted its liver-protective potential during chemotherapy for leukemia. (19)
Milk thistle phytosome can be used as a supportive treatment for:
• Functional and pathological liver disorders
• Acute and chronic hepatitis
• Liver cirrhosis
• Fatty liver disease
• Liver toxicity
References
1 Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs. 2001;15:465-489.
2 Ferenci P, Dragosics B, Dittrich H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol. 1989;9:105-113.
3 Pares A, Planas R, Torres M, et al. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. J Hepatol. 1998;28:615-621.
4 Ina Bergheim, Craig J. McClain, and Gavin E. Arteel. Treatment of Alcoholic Liver Disease. Dig Dis. 2005; 23(3-4): 275–284.
5 Skottova N, SVagera Z, Vecera R, Urbanek K, Jegorov A, Simanek V. Pharmacokinetic study of iodine-labeled silibinins in rat. Pharmacol Res. 2001;44:247-253.
6 Lieber CS. Alcoholic liver disease: new insights in pathogenesis lead to new treatments. J Hepatol. 2000;32:113-128.
7 Vogel G, Tuchweber B, Trost W, Mengs U. Protection by silibinin against Amanita phalloides intoxication in beagles. Toxicol Appl Pharmacol. 1984;73:355-362.
8 Carmela Loguercio and Davide Festi. Silybin and the liver: From basic research to clinical practice. World J Gastroenterol. 2011 May 14; 17(18): 2288–2301.
9 Sonnenbichler J, Scalera F, Sonnenbichler I, Weyhenmeyer R. Stimulatory effects of silibinin and silicristin from the milk thistle Silybum marianum on kidney cells. J Pharmacol Exp Ther. 1999;290:1375-1383.
10 Bokemeyer C, Fels LM, Dunn T, et al. Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity. Br J Cancer. 1996;74:2036-2041.
11 Kumaraguruparan Ramasam, Rajesh Agarwal. Multitargeted therapy of cancer by silymarin. Cancer Lett. 2008 Oct 8; 269(2): 352–362.
12 Barzaghi N, Crema F, Gatti G, Pifferi G, Perucca E. Pharmacokinetic studies on IdB 1016, a silybin- phosphatidylcholine complex, in healthy human subjects. Eur J Drug Metab Pharmacokinet. 1990 Oct-Dec;15(4):333-8.
13 P. Morazzoni, A. Montalbetti, S. Malandrino, G. Pifferi. Comparative pharmacokinetics of silipide and silymarin in rats. European Journal of Drug Metabolism and Pharmacokinetics; September 1993, Volume 18, Issue 3, pp 289-297.
14 Bombardelli E, Curri SB, Della Loggia R, et al. Complexes between phospholipids and vegetal derivatives of biological interest. Fitoterapia 1989;90:1-9.
15 Kidd PM. Phosphatidylcholine (Monograph). In: Czap K, Miller AL, Head KA, et al, eds. Alternative
Medicine Review Monographs Volume One. Dover, 2002:310-315.
16 Kidd, Kathleen Head. A Review of the Bioavailability and Clinical Efficacy of Milk Thistle Phytosome: A Silybin-Phosphatidylcholine Complex (Siliphos®). Alternative Medicine Review; Volume 10, Number 3, 2005.
17 Loguercio C. et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: A randomized controlled trial; Free Radical Biology and Medicine (02/2012; 52(9):1658-65).
18 Buzzelli G, Moscarella S, Giusti A, et al. A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB 1016) in chronic active hepatitis. Int J Clin Pharmacol Ther Toxicol. 1993;31:456-460.
19 Ladas, Elena J. MS, RD et al. “A randomized, controlled, double-blind, pilot study of milk thistle for treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL)”. Cancer. 01/2010; 116(2):506-13.
For a complete cure,
Solage recommends:
Solage recommends:
Synergy Bundle for Digestion - Liver and Gut Health
Detox - Digestion
Liposomal liquid glutathione
Our liposomal formulas
FAQ (questions fréquentes)
- Most of our nutrients come from France or Europe (local is a priority), except when we can't do otherwise (for curcuma, for example). We never choose ingredients from places or countries where quality is not assured and workers are poorly paid.
- Solage products are designed in France and manufactured according to GMP (Good Manufacturing Practice) standards from the pharmaceutical industry and the HACCP (Hazard Analysis Critical Control Point) method, developed by NASA.
Both methods implement procedures, documents and controls to guarantee perfect traceability and the absence of biological or chemical contamination.
- Solage is a French company, and its products are registered with the relevant authorities.
Solage products are safe, with no bad surprises.
To answer this question, we distinguish between three types of product, depending on their nature and intended purpose:
1/ Ideally taken as a continuous treatment: those which compensate for a nutritional or age-related deficiency, and which serve to restore the body's functions without altering its normal metabolism.
- Common nutritional deficiencies: marine omega-3, vitamin C, magnesium, vitamin D between October and May
- Age-related or pathological deficiencies: Ubiquinol, Glutathione, Iron, Collagen (type I and II)
- To help the body deal with underlying problems: Saffron, Ashwagandha, Men's and women's urinary comfort, cholesterol
2/ To be taken in a cure, but where a break is not necessarily necessary if you or your healthcare professional find it useful:
Detox: Milk thistle, Glutathione
Digestion: Probiotics
3/ Products where a break is useful:
- Curcumin: at least a break of a few days between each box, as it modifies metabolic pathways in the body
- Echinacea (immunity): a break of a few days between each box so as not to over-stimulate the immune system
- Melatonin: avoid taking it every day over the long term, so as not to habituate the body.
In all cases, it's important to remember that the products we offer are genuinely active, that it's important to respect dosage and that they are not a substitute for a varied, balanced diet and a healthy lifestyle.
This will of course depend on the product and your physiological state.
It's worth remembering that physiology is a long-term process, and that it generally takes two to three months, sometimes longer, to achieve a profound change.
However, the feeling is generally quicker, between 15 days and two months.It is then necessary to continue to try to fix these initial results in greater depth.
However, this will be much quicker with subsequent products:
- Melatonin and sublingual GABA, which have a very rapid onset of action (between two minutes and 30 minutes)
- Probiotics (48 hours to two weeks))
Please refer to the “Scientific studies” section of this product page, where you'll find most studies on bioavailability and medium-term effects.
