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Coenzyme Q10: Ubiquinol Kaneka - Solquinol
€29.90
DLUO : 31/05/27
Shipped on : 22 January 2025
+ A powerful intracellular antioxidant with anti-aging action at the cellular level (mitochondria),
+ Supports energy metabolism, reduces fatigue, and promotes heart and blood vessel function: enhances athletic performance,
+ Box of 30 capsules containing 100mg (1 month supply) of Kaneka Ubiquinol in a liquid matrix: 10 times more bioavailable than dry CoQ10 powder,
Ubiquinol (reduced Coenzyme Q10) is a crucial component for the body's energy production.
It plays a key role in the mitochondria during the Krebs cycle.
Mitochondria act like energy powerhouses within our cells, producing ATP (Adenosine triphosphate). ATP is the body's energy currency. When a muscle moves, it uses ATP and breaks it down into ADP. During the Krebs cycle, mitochondria convert ADP back into ATP to power the muscles.
Without Ubiquinol, the mitochondria cannot complete the Krebs cycle and therefore cannot produce ATP.
The body stores two forms of Coenzyme Q10: ubiquinone (the oxidized form) and ubiquinol (the reduced form). Ubiquinol is the more prevalent form.
The ability to convert ubiquinone into ubiquinol decreases with age, under certain conditions that increase oxidative stress (such as liver disease, kidney disease, heart conditions, and diabetes), and in individuals taking cholesterol-lowering medications (both chemical and natural statins).
Additionally, lower levels of Ubiquinol are found in those engaging in intensive physical activity.
Ubiquinol is also a powerful intracellular antioxidant
It is uniquely capable of neutralizing free radicals inside our cells, especially those generated during the Krebs cycle. Free radicals are highly reactive molecules implicated in the development of cardiovascular diseases, certain cancers, and other age-related illnesses.
However, this Ubiquinol needs to be pure, easily absorbed by the body, and in the right dosage.
Solquinol contains 100 mg of Ubiquinol, the Coenzyme Q10 form that is often lacking.
100 mg is the optimal dosage to quickly restore and then sustainably maintain healthy blood levels of Ubiquinol.
Solquinol’s Ubiquinol is highly absorbable because it is in a liquid form emulsified in a lecithin oil matrix, with its bioavailability tested.
Note: Supplementing with non-reduced Coenzyme Q10, even at doses of 200 mg or higher per day, is ineffective because the body cannot convert it into biologically active Ubiquinol.
Moreover, only reduced Coenzyme Q10 truly has antioxidant properties.
Solquinol contains Kaneka™ Ubiquinol, the only scientifically proven effective source. It is pure, directly absorbable by the body, and ready for use by the mitochondria without prior conversion.
Caution: Some may be tempted to sell non-certified Kaneka™ Ubiquinol, but unfortunately, the quality is often lacking.
Why Choose Solquinol Over Other Coenzyme Q10 Supplements?
• Solquinol contains the reduced form of coenzyme Q10, directly usable by the body and twice as bioavailable as ubiquinone (the oxidized form). Its bioavailability is further enhanced through its delivery in a lecithin oil matrix.
• Solquinol provides 100mg of Ubiquinol, the optimal dosage to quickly restore blood levels of Ubiquinol.
• Solquinol contains Kaneka QH™ Ubiquinol, the first bioavailable Ubiquinol on the nutritional supplement market, which is scientifically tested.
• Kaneka QH™ Ubiquinol is made up of a 100% All-trans isomer, the biologically active form of coenzyme Q10 (without cis-isomers).
• Product safety has been demonstrated through controlled human research using placebo comparisons. Its bioavailability is twice as high as that of ubiquinone.
• Solquinol is enhanced with Vitamin B1 and Vitamin C for optimized action: Vitamin B1 supports energy metabolism and contributes to normal heart function. Vitamin C helps reduce fatigue and supports healthy collagen formation for normal blood vessel function.
Box of 30 capsules (1-month supply)
Ingredients per marine capsule (recommended daily intake)
Ubiquinol (Kaneka QHTM) in an oil matrix with lecithin (98% all-trans isomer; free from cis isomers): 100 mg
Vitamin C (L-ascorbic acid): 12 mg (15% NRV)
Vitamin B1 (thiamine mononitrate): 0.6 mg (55% NRV)
Allergen: soy
1 capsule once or twice a day
The dosage can be increased to 2 capsules three times a day during the first two weeks of treatment to boost blood levels.
It is recommended to take Solquinol for at least 2 months or over longer periods for enhanced effectiveness, unless otherwise advised by your healthcare professional.
Possible side effects
No known side effects exist for the indicated dosage.
Coenzyme Q10 may enhance the action of antidiabetic and antihypertensive medications. Therefore, monitoring is recommended when used simultaneously. It may also reduce the effect of oral anticoagulants.
The consumption of Solquinol does not affect the body's ability to produce coenzyme Q10.
When to Use Solquinol?
• When the body's natural ability to convert ubiquinone (coQ10 (ox)) into ubiquinol (coQ10H2 (red)) is reduced or insufficient:
> for individuals over the age of 45
> in cases of extreme oxidative stress to protect against free radicals – sometimes due to underlying conditions
> for people taking cholesterol-lowering medication, such as statins
> for those engaged in intensive sports activities
> as a preventive measure for migraines
> in cases of heart failure
> for high blood pressure
• When experiencing a loss of vitality and to prevent aging due to its support of energy metabolism
• To support the heart and blood vessels, particularly for its positive effect on blood pressure
• For maintaining flexible muscles
All these situations can lead to fatigue and difficulty with physical exertion.
• For male infertility caused by a reduced sperm count, abnormal shape, or insufficient motility (ability to move)
Additional Tips
- To enhance heart and blood vessel health, or for high blood pressure, it is recommended to combine Solquinol with Solakrill's highly assimilable omega-3s.
- For mobility issues, it is advised to pair Solquinol with Solumine, the natural anti-inflammatory turmeric phytosome.
- For athletes, combining Solquinol with Solumine and Solakrill is recommended to sustainably improve physical condition.
Information, Scientific Studies, and Dosage for Specific Situations
Coenzyme Q10 exists as a redox pair: ubiquinol in its reduced form and ubiquinone in its oxidized form. Ubiquinol acts as the antioxidant in this pair. Both forms (ubiquinone and ubiquinol) play a crucial role in cellular energy production.
In young and relatively healthy individuals, over 80% of the total coenzyme Q10 levels
in the plasma, intestines, and liver consist of ubiquinol. The reduced form predominates. Enzymes (reductases) maintain ubiquinol's dominance, even after oral administration of ubiquinone.
Ubiquinol versus Ubiquinone Levels Over Time
Between the ages of 20 and 45, under normal circumstances, ubiquinone use (CoQ10 (ox)) remains sufficient. In older individuals, the ratio of ubiquinone to ubiquinol significantly increases in the plasma. This may be due to increased oxidative stress, less efficient conversion of ubiquinone to ubiquinol, or both (1). Using ready-to-absorb ubiquinol can help restore the balance between the reduced and oxidized forms.
From age 55 onwards, taking ubiquinol is recommended.
Studies have also shown an imbalance toward ubiquinone deficiency in patients with hepatitis, cirrhosis, or hepatoma (2), as well as in pre-diabetic or diabetic individuals (3).
Ubiquinol Use in Heart Failure
An example of extreme oxidative stress is demonstrated in a human study (4) involving 7 patients with advanced congestive heart failure. Using 450 mg of ubiquinone (ox) per day resulted in sub-therapeutic CoQ10 levels (1.6 μg/ml, while a minimum level of 3.5 μg/ml is required (tt)) in their plasma. Switching to 580 mg of ubiquinol (red) per day increased plasma CoQ10 levels from an average of 1.5 to 6.5 μg/ml. Cardiac contractility improved (ejection fraction rose from an average of 22% to 39%), and clinical improvement was notable, with patients moving from NYHA class IV to class II on average.
Ubiquinol and Statins
It has been shown that cholesterol-lowering medications reduce plasma ubiquinol levels (5). This reduction likely explains the muscle pain experienced by many patients. Taking 100 to 200 mg of ubiquinol daily can reduce this pain by up to 40% (6, 7, 8).
Ubiquinol in High-Intensity Sports
In athletes, a double-blind, placebo-controlled study (9) involving 100 individuals preparing for the London 2012 Olympics showed that taking 300 mg of ubiquinol daily, alongside a structured training program, increased peak power output by 11%, compared to 8% in the placebo group (p<0.03).
Aging Prevention
Other studies suggest that daily ubiquinol supplementation may prevent aging effects. A study (10) on an accelerated aging mouse model (SAMP1) showed that ubiquinol administration reduced senescence in middle-aged mice.
Male and Female Fertility
Semen contains high amounts of ubiquinol, which supports sperm motility and acts as an antioxidant.
A study on 264 male patients with fertility issues (low sperm count, poor motility, and abnormal morphology) showed that 200 mg of Kaneka Ubiquinol daily significantly increased sperm count in 62% of men, motility in 57%, and normal sperm morphology in 52% (11).
Another study on 60 male volunteers, taking 150 mg/day, produced similar results, with a 53% increase in sperm count.
In women, oxidative stress has been shown to reduce egg quality. Eggs contain nearly 200 times more mitochondria than typical cells, and a link has been established between mitochondrial quantity and fertilization potential. Ubiquinol supplementation is being studied to enhance egg quality, especially in older women trying to conceive.
Proven Safety
The safety of Kaneka QH® Ubiquinol has been validated, with studies showing it is twice as bioavailable as ubiquinone (12, 13).
Dosage Recommendations:
• For various mitochondrial dysfunctions (coordination issues, Alzheimer's, Parkinson's, Huntington's): 4 to 15 mg/kg body weight daily
• To support heart function by enhancing energy production in cardiac muscle cells: 200 to 300 mg per day with meals
• For high blood pressure: 100 to 200 mg per day with meals
• For those taking cholesterol-lowering medications: 100 to 200 mg per day with meals
• To protect against LDL cholesterol oxidation: 100 mg per day with meals
• For ischemia (angina): 200 to 300 mg per day with meals
• For cardiac arrhythmia: 200 to 300 mg per day with meals
• For gum disease: 100 mg per day with meals
• To aid with male or female infertility: 200 to 300 mg per day with meals.
Références
1 Wada H, Goto H, Hagiwara S, Yamamoto Y. Redox status of coenzyme Q10 is associated with chronological age. Am Geriatr Soc 2007; 55(7):1141-2.
2 Yamamoto Y, Yamashita S. Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion. Biofactors 1999; 9(2-4):241-6.
3 Lim SC, Lekshminarayanan R, Goh SK, Ong YY, Subramaniam T, Sum CF, Ong CN, Lee BL. The effect of coenzyme Q10 on microcirculatory endothelial function of subjects with type 2 diabetes mellitus. Atherosclerosis 2008; 196(2):966-9.
4 Langsjoen PH, Langsjoen AM. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors. 2008;32(1-4):119-28.
5 Langsjoen PH et al.Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors 2005; 25(1- 4):147-52.
6,7,8 Stroke. 2007;38:2652-2657
7 Drug Safety 2007; 30
8 Am J Cardiol 2007 ;99 :1409-1412
9 Dietmar Alf1 Michael E Schmidt, and Stefan C Siebrecht.Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study.J Int Soc Sports Nutr. 2013; 10: 24
10 Yan J, Fujii K, Yao J, Kishida H, Hosoe K, Sawashita J, Takeda T, Mori M, Higuchi K.Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice.Exp Gerontol. 2006 Feb;41(2):130-40.
11 Safarinejad MR1, Safarinejad S, Shafiei N, Safarinejad S. Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study. J Urol. 2012 Aug;188(2):526-31
12 Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M. Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol 2007; 47(1):19-28.
13 Langsjoen PH, Langsjoen AM. Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clin Pharmacol Drug Dev. 2014 Jan;3(1):13-7.
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FAQ (questions fréquentes)
- Most of our nutrients come from France or Europe (local is a priority), except when we can't do otherwise (for curcuma, for example). We never choose ingredients from places or countries where quality is not assured and workers are poorly paid.
- Solage products are designed in France and manufactured according to GMP (Good Manufacturing Practice) standards from the pharmaceutical industry and the HACCP (Hazard Analysis Critical Control Point) method, developed by NASA.
Both methods implement procedures, documents and controls to guarantee perfect traceability and the absence of biological or chemical contamination.
- Solage is a French company, and its products are registered with the relevant authorities.
Solage products are safe, with no bad surprises.
To answer this question, we distinguish between three types of product, depending on their nature and intended purpose:
1/ Ideally taken as a continuous treatment: those which compensate for a nutritional or age-related deficiency, and which serve to restore the body's functions without altering its normal metabolism.
- Common nutritional deficiencies: marine omega-3, vitamin C, magnesium, vitamin D between October and May
- Age-related or pathological deficiencies: Ubiquinol, Glutathione, Iron, Collagen (type I and II)
- To help the body deal with underlying problems: Saffron, Ashwagandha, Men's and women's urinary comfort, cholesterol
2/ To be taken in a cure, but where a break is not necessarily necessary if you or your healthcare professional find it useful:
Detox: Milk thistle, Glutathione
Digestion: Probiotics
3/ Products where a break is useful:
- Curcumin: at least a break of a few days between each box, as it modifies metabolic pathways in the body
- Echinacea (immunity): a break of a few days between each box so as not to over-stimulate the immune system
- Melatonin: avoid taking it every day over the long term, so as not to habituate the body.
In all cases, it's important to remember that the products we offer are genuinely active, that it's important to respect dosage and that they are not a substitute for a varied, balanced diet and a healthy lifestyle.
This will of course depend on the product and your physiological state.
It's worth remembering that physiology is a long-term process, and that it generally takes two to three months, sometimes longer, to achieve a profound change.
However, the feeling is generally quicker, between 15 days and two months.It is then necessary to continue to try to fix these initial results in greater depth.
However, this will be much quicker with subsequent products:
- Melatonin and sublingual GABA, which have a very rapid onset of action (between two minutes and 30 minutes)
- Probiotics (48 hours to two weeks))
Please refer to the “Scientific studies” section of this product page, where you'll find most studies on bioavailability and medium-term effects.
