Solaflex Joints: Collagen, MSM...
Joint Support Supplement, Collagen - Solaflex | Solage
Joint Support Supplement, Collagen - Solaflex | Solage
Solaflex Joints: Collagen, MSM...
Joint Support Supplement, Collagen - Solaflex | Solage
Joint Support Supplement, Collagen - Solaflex | Solage

Joints : Collagen, MSM - Solaflex

€46.90
BBD : 01/31/2027
Shipped on : 10 February 2025

+ For athletes and seniors: Deep regeneration with a pain-relief action targeting the three key dimensions of joint health: cartilage, tendons, and synovial fluid.

+ Type 2 native collagen (non-hydrolyzed and sourced from chicken) and biologically active, combined with hyaluronic acid, chondroitin, and glucosamine: cartilage reconstruction.

+ Mucopolysaccharides, Type 1 collagen (low-molecular-weight hydrolyzed marine) and Vitamin C: tendon flexibility. Purified MSM, Boswellia Serrata extract, and manganese: pain reduction.

+ Box of 90 capsules. Duration: 1 month (3 caps/day). Vegan

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Joints : Collagen, MSM - Solaflex
Joints : Collagen, MSM - Solaflex

Solaflex is a fusion of multiple active ingredients. This natural combination helps regenerate joints and supports individuals in regaining proper mobility.

Today in France, nearly 9 out of 10 people suffer from joint problems.

Joint issues are even the second leading cause of medical consultations in developed countries. Faced with these physical challenges, Solaflex stands out as a preferred, effective, and natural solution, all with no side effects.

The cause of joint pain?

Age is the primary cause of joint problems. From the age of 40 and especially after 65, joint issues become increasingly common. Joint problems are generally defined by a severe lack of cartilage. This progressive cartilage loss is, in most cases, caused by:

  • Aging
  • Metabolic disorders
  • Excessive pressure
  • Genetic predisposition
  • Natural cartilage fragility

Besides cartilage deterioration, joint pain caused by aging or intense sports activity has two other main origins:

  • Tendons that stiffen and become inflamed, restricting movement
  • The loss of synovial fluid. Essential for the body, this fluid acts as the lubricant for the joint mechanism. Without it, friction increases...

Finally, joint pain falls into two main categories: inflammatory and mechanical. Whether inflammatory or mechanical, these types of pain typically share the same symptoms:

  • Joint stiffness, often after periods of inactivity or in the morning
  • Swelling or redness
  • A warm sensation in the joint
  • Reduced flexibility
  • Loss of mobility

Solaflex: What Exactly Is It?

Solaflex is a comprehensive formula designed to address the three key causes of joint pain. Developed by Laboratoire Solage, this product is a specialized dietary supplement for joint health.

Ideal for seniors and athletes, Solaflex is also a natural solution that supports mobility, flexibility, and cartilage regeneration. Available in capsule form, with 90 capsules per bottle, Solaflex combines various natural active ingredients, each offering its own unique nutritional benefits.

  • Methylsulfonylmethane (MSM): MSM is a sulfur-containing organic compound naturally found in the body and certain foods. The sulfur in MSM helps alleviate and address joint pain.
  • Chondroitin Sulfate (Glycosaminoglycan): This molecule is found in the body's connective and cartilage tissues. It plays a key role in maintaining the structure and elasticity of cartilage, tendons, and skin.
  • Eggshell Membrane: The eggshell membrane is an incredibly beneficial nutritional source. It helps maintain joint tissue flexibility, including tendons, ligaments, and cartilage. Additionally, it is a natural source of glucosamine, chondroitin, collagen, and hyaluronic acid.
  • Vitamin C: A water-soluble antioxidant vitamin, vitamin C not only supports cardiovascular health but also contributes to the well-being of bones, cartilage, teeth, and gums.
  • Boswellia Serrata: A natural anti-inflammatory used in Ayurvedic medicine, Boswellia Serrata (also known as Indian frankincense) is a tree native to India. Its trunk and resin may support bone, joint, and muscle endurance.
  • Type I & Type II Collagen: Type I collagen is primarily known for its benefits to the skin, but it is also a major component of tendons, organs, and cartilage. Type II collagen is essential for cartilage regeneration. Notably, Type I collagen is hydrolyzed (broken down with water) for better absorption, while Type II collagen is in its native form—the only form that can prevent cartilage degradation by the immune system (Peyer’s patches).
  • Cartilage Extract: Cartilage acts as a cushion and provides support to joints under stress.
  • Manganese: An essential trace element, manganese plays a crucial role in the body's overall function and contributes to cartilage synthesis.

What Are the Real Benefits of Certain Extracts for Joint Health?

As previously mentioned, the active ingredients in Solaflex help improve joint mobility, protect against joint wear, and support the health of cartilage, bones, and other organs. These claims are backed by several studies. Here are some of them:

Methylsulfonylmethane (MSM)

Discovered in 1970 by American researchers, this sulfur compound takes the form of a bitter-tasting white powder once the chemical process (oxidation) is complete. However, methylsulfonylmethane originates from a natural raw material: wood pulp. This sulfur mineral is found in small amounts in various foods:

  • Fruits
  • Vegetables
  • Meat
  • Seafood
  • Chocolate
  • Dairy products
  • Cheese

Methylsulfonylmethane has several benefits for the human body:

  • Helps maintain the proper function of joints, tendons, and ligaments
  • Supports cartilage regeneration and nourishment
  • May be beneficial for bone and joint health
  • Nourishes joints and aids in collagen synthesis within joint cartilage
  • Has a positive effect on teeth, nails, hair, and bones
  • Essential for collagen production and the proper formation of cartilage and bone tissue

To demonstrate that MSM does not cause adverse effects, a 16-week study conducted in 2019 examined the effects of methylsulfonylmethane. Participants consumed 6g of MSM per day, with researchers monitoring metabolic parameters to determine whether MSM altered hematological, liver, or kidney function. They also assessed physiological parameters such as blood pressure and weight.

Conclusion: The study found that MSM had no impact on white blood cells, platelets, hemoglobin, total bilirubin, aspartate aminotransferase, alanine aminotransferase, creatinine levels, diastolic or systolic blood pressure, or body weight. Based on these findings, regular MSM intake does not cause adverse effects or side effects on the body. (1.)

Chondroitin Sulfate

A key component of bone and cartilage, chondroitin sulfate is a glycosaminoglycan. In the body, its role is to maintain osmotic pressure and help hydrate cartilage. Regarding the human skeleton, it contributes to flexibility and elasticity of the bones.

According to a study published in December 2014, chondroitin sulfate and glucosamine sulfate have beneficial effects on the metabolism of in vitro models of synovial joint cells. Regarding the knee, results show a slight but significant reduction in the rate of joint space narrowing, which is associated with joint pain relief.

Chondroitin sulfate and glucosamine sulfate are recommended by several international medical guidelines for managing knee and hip conditions. However, some guidelines do not endorse these supplements, or only recommend them under certain conditions. (2.)

Eggshell Membrane

An agricultural product derived from animal farming, the egg is a highly nutritious food. In the past, extracting and properly using eggshell membranes was a challenge. Long before scientific validation, legends and rumors circulated about the beneficial properties of eggshell membranes for joint health.

According to legend, samurais prepared a decoction made from eggshell membranes to prevent joint pain. As it turns out, this was not just a myth—science has demonstrated that eggshell membrane is a 100% natural and bioavailable source of collagen, hyaluronic acid, glucosamine, and chondroitin. These nutrients contribute to reducing physical fatigue and helping maintain healthy bones and joints.

A study published in 2009 investigated the viability, effectiveness, and safety of eggshell membrane as a treatment for pain and stiffness associated with joint and connective tissue disorders. The results were conclusive: Natural eggshell membrane is a promising new therapeutic option. With a daily dose of 500 mg, pain was significantly reduced both rapidly (within seven days) and consistently (over 30 days). (3.)

Manganese

Manganese is a trace element (a small but essential mineral nutrient) that plays a crucial role in bone formation. One of its key functions is directly supporting cartilage synthesis. Additionally, it neutralizes free radicals, which are known to trigger inflammation.

Vitamin C

Found naturally in various fruits and vegetables, vitamin C (also known as ascorbic acid) is essential for maintaining overall health. Since the human body cannot synthesize or store vitamin C, it must be consumed regularly. Simply put, vitamin C is critical for collagen production.

Type I and II Collagen

A naturally occurring substance, type I collagen is abundantly present in the human body. It is found in cartilage, bones, and tendons, but its benefits go beyond that. Type I collagen also provides skin with its elasticity and resilience. In total, there are around 30 different types of collagen.

Type II collagen makes up 50% of the cartilage in tendons and ligaments, making it essential for overall joint health. Joint pain and injuries are often linked to a decline in type II collagen. (5.)

Cartilage Extract

Dense and elastic, cartilage is a connective tissue that covers bones, helping to reduce friction between them. Although present in limited amounts in the human body, cartilage is crucial for preventing joint issues.

What Are Our Joints Made Of?

Bones, cartilage, tendons, and ligaments contain an extracellular matrix made of collagen and proteoglycans.

Proteoglycans are composed of hyaluronic acid and mucopolysaccharides, including chondroitin sulfate and glucosamine.

What Type of Collagen is in Our Joints? How Much Proteoglycans?

- Tendons and ligaments contain a high amount of collagen, mainly type 1, but have low levels of proteoglycans.

- Cartilage has less collagen but mostly type 2 and a high concentration of proteoglycans.

Therefore, to support the proper formation and maintenance of bones, cartilage, tendons, and ligaments, a sufficient intake of type 1 and type 2 collagen and proteoglycans is essential.

Solaflex provides the optimal amount of proteoglycans (hyaluronic acid, glucosamine, and chondroitin) and non-denatured type 1 and type 2 collagen.

Why Non-Denatured Type 2 Collagen Instead of Hydrolyzed?

Most nutritional supplements typically contain hydrolyzed type 2 collagen.

While it's inexpensive, it is also less effective because the process alters the protein's molecular structure by destroying its triple helix.

As a result, this collagen completely loses its immunomodulatory properties.

Non-denatured type 2 collagen, also known as native collagen, is biologically identical to the collagen found in our cartilage.

Its main benefit, aside from being readily usable by the body, is its immunomodulatory capability:

When cartilage is damaged, waste is produced, which the immune system targets using pro-inflammatory molecules called cytokines.

Unfortunately, these molecules can continue to attack healthy cartilage, causing inflammation.

Native type 2 collagen helps to desensitize these defenses, allowing for a positive cycle of cartilage rebuilding and inflammation reduction.

What Other Ingredients Are in Solaflex?

- Boswellia Serrata (frankincense tree), standardized in AKBA and free from harmful beta boswellic acid. Frankincense helps maintain joint flexibility by reducing tissue damage and pro-inflammatory compounds.

- Highly pure MSM (a sulfur source),

- Vitamin C, which supports collagen formation,

- Manganese, which helps maintain healthy bones and normal connective tissue formation (proteoglycans).

Box of 90 capsules (1 month supply)

Active ingredients per day (3 capsules)

  • Methylsulfonylmethane (MSM): 450 mg
  • Mucopolysaccharides: 395.4 mg
  • Eggshell membrane: 300 mg
  • Vitamin C: 253.59 mg (106% RDI) including L-ascorbic acid: 195 mg and Sodium L-ascorbate: 28.59 mg
  • Boswellia Serrata: 180 mg. Oleoresin standardized to 18 mg of acetyl-11-keto-beta-boswellic acid (does not contain beta boswellic acid, which is harmful)
  • Type I collagen (low molecular weight hydrolyzed marine collagen): 70.35 mg
  • Cartilage extract from chicken sternum: 40.5 mg standardized to 25% undenatured type II collagen
  • Manganese: 0.99 mg (49.5% RDI), including Manganese Sulfate: 0.57 mg and Manganese Bisglycinate: 0.42 mg

RDI: Reference Daily Intake

Allergen: Egg

Take 1 capsule three times a day, preferably before meals, unless otherwise advised by your healthcare professional.

• Do not use if you have an egg allergy

When to Use Solaflex?

• For joint pain, including arthritis, rheumatoid arthritis, and similar conditions,

• To improve joint flexibility,

• To help preserve damaged cartilage due to aging or intense sports activities,

• For stiffness or tendon inflammation (tendonitis),

• To support the normal formation of collagen, bones, and connective tissues

Combining Mucopolysaccharides, Type 1 Collagen, and Vitamin C for Tendinopathy

Tendinopathy is a common sports injury affecting tendon structure. It results in not only pain but also disrupted collagen fiber formation, leading to a thicker, swollen tendon.

A 90-day multicenter open study was conducted on 98 patients with tendinopathy (Achilles, knee, or elbow tendon).

Participants tested a blend of mucopolysaccharides (435mg), type 1 collagen (75mg), and vitamin C (60mg).

After 90 days, the following results were observed:

1 / Pain Reduction

- 80% pain reduction for Achilles tendon

- 73% pain reduction for knee

- 81% pain reduction for elbow

2 / 50% Improvement in Joint Function for all groups (Achilles, knee, and elbow tendon).

3 / Reduced tendon thickness and structural restoration across all groups (Achilles, knee, and elbow tendon).

Eggshell Membrane is Effective for Osteoarthritis Patients

Eggshell membrane naturally contains collagen, hyaluronic acid, chondroitin sulfate, glucosamine, proteins, and sulfur amino acids.

20 patients with osteoarthritis took 300mg of eggshell membrane daily for 50 days.

At the end of the study:

- 70% of patients experienced at least a 20% reduction in pain,

- 95% reported at least a 20% improvement in joint function,

- 95% noted a 60% reduction in stiffness.

Eggshell Membrane is Beneficial for Joint Pain in Athletes and Seniors

A study was conducted with 30 athletes (15 runners and 15 crossfitters) and 30 sedentary seniors.

The test lasted 30 days for athletes and 50 days for seniors.

Average improvements observed were:

- 53% reduction in pain

- 52% reduction in stiffness

- 46% improvement in physical function

Native Type 2 Collagen Helps Reduce Knee Osteoarthritis Symptoms

A study involving knee osteoarthritis patients (ages 49 to 66) compared supplementation with native type 2 collagen (2 x 10mg/day) combined with acetaminophen versus acetaminophen alone.

After 3 months, the group receiving native type 2 collagen showed significantly better control of symptoms.

References

1. Methylsulfonylmethane for treatment of low back pain: A safety analysis of a randomized, controlled trial

Paul Crawford, Amanda Crawford, Frederick Nielson, Robert Lystrup

2. What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis?

Yves Henrotin, Marc Marty, Ali Mobasheri

3. Eggshell membrane: A possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies

Kevin J Ruff, Dale P DeVore, Michael D Leu and Mark A Robinson

4. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee

Muhammed Majeed, Shaheen Majeed, Narayanan K Narayanan, Kalyanam Nagabhushanam

5. Molecular Cell Biology, 4th edition

Harvey Lodish, Arnold Berk, S Lawrence Zipursky, Paul Matsudaira, David Baltimore, and James Darnell.

6. Blasco M-IJ, Aguirre A, Gil-Quintana E, Fenaux M. J Ost Arth 2016;1

7. Bakilan F, Armagan O, Ozgen M et al. Euras J Med 2016; 48:95-101.

FAQ
FAQ (questions fréquentes)

- Most of our nutrients come from France or Europe (local is a priority), except when we can't do otherwise (for curcuma, for example). We never choose ingredients from places or countries where quality is not assured and workers are poorly paid.

- Solage products are designed in France and manufactured according to GMP (Good Manufacturing Practice) standards from the pharmaceutical industry and the HACCP (Hazard Analysis Critical Control Point) method, developed by NASA.

Both methods implement procedures, documents and controls to guarantee perfect traceability and the absence of biological or chemical contamination.

- Solage is a French company, and its products are registered with the relevant authorities.

Solage products are safe, with no bad surprises.

To answer this question, we distinguish between three types of product, depending on their nature and intended purpose:

1/ Ideally taken as a continuous treatment: those which compensate for a nutritional or age-related deficiency, and which serve to restore the body's functions without altering its normal metabolism.

- Common nutritional deficiencies: marine omega-3, vitamin C, magnesium, vitamin D between October and May

- Age-related or pathological deficiencies: Ubiquinol, Glutathione, Iron, Collagen (type I and II)

- To help the body deal with underlying problems: Saffron, Ashwagandha, Men's and women's urinary comfort, cholesterol

2/ To be taken in a cure, but where a break is not necessarily necessary if you or your healthcare professional find it useful: 

Detox: Milk thistle, Glutathione

Digestion: Probiotics

3/ Products where a break is useful:

- Curcumin: at least a break of a few days between each box, as it modifies metabolic pathways in the body

- Echinacea (immunity): a break of a few days between each box so as not to over-stimulate the immune system

- Melatonin: avoid taking it every day over the long term, so as not to habituate the body.

In all cases, it's important to remember that the products we offer are genuinely active, that it's important to respect dosage and that they are not a substitute for a varied, balanced diet and a healthy lifestyle.

This will of course depend on the product and your physiological state.

It's worth remembering that physiology is a long-term process, and that it generally takes two to three months, sometimes longer, to achieve a profound change.

However, the feeling is generally quicker, between 15 days and two months.It is then necessary to continue to try to fix these initial results in greater depth.

However, this will be much quicker with subsequent products:

- Melatonin and sublingual GABA, which have a very rapid onset of action (between two minutes and 30 minutes)

- Probiotics (48 hours to two weeks))

Please refer to the “Scientific studies” section of this product page, where you'll find most studies on bioavailability and medium-term effects.